Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ODC1 | P11926 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 5/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765128 | 1.00 | ARG1 (0.40) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL20764738 | 0.82 | MEN1 (0.55) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL20764740 | 0.82 | MEN1 (0.55) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL2910123 | 0.79 | ALDH1A1 (0.36) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL2910118 | 0.79 | ALDH1A1 (0.36) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL509976 | 0.75 | ALDH1A1 (0.48) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL27459648 | 0.74 | ALDH1A1 (0.65) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL5949968 | 0.71 | ODC1 (0.64) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL24066748 | 0.69 | MEN1 (0.48) | ARG1ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL28623644 | 0.69 | PTGS1 (0.38) | ALDH1A1CYP2C19LMNASLC6A6BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3673056-A1 | DETERGENT COMPOSITIONS COMPRISING GH9 ENDOGLUCANASE VARIANTS II | Henkel AG & Co. KGaA (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019038059-A1 | DETERGENT COMPOSITIONS COMPRISING GH9 ENDOGLUCANASE VARIANTS II | HENKEL AG & CO. KGAA (DE) | 2019-02-28 | — | — | WO | disclosed |