Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA4 | P22748 | 10/20 | 0.48 |
| ▸ | CA9 | Q16790 | 10/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970784 | 0.77 | MGLL (0.59) | MGLLBCHEACHECHEK2HPGD | |
| SCHEMBL21843704 | 0.77 | HPGD (0.70) | MGLLCHEK2HPGD | |
| SCHEMBL16619560 | 0.76 | MGLL (0.65) | MGLLCHEK2HPGD | |
| SCHEMBL19986744 | 0.75 | MGLL (0.57) | MGLLBCHEACHECHEK2HPGD | |
| SCHEMBL16631031 | 0.73 | MGLL (0.60) | MGLLBCHEACHECHEK2HPGD | |
| SCHEMBL20765523 | 0.72 | MGLL (0.58) | MGLLBCHEACHECHEK2HPGD | |
| SCHEMBL20765507 | 0.72 | CHEK2 (0.58) | MGLLBCHEACHECHEK2HPGD | |
| SCHEMBL20765786 | 0.72 | BCHE (0.55) | MGLLBCHEACHECHEK2 | |
| SCHEMBL19970751 | 0.72 | BCHE (0.55) | MGLLBCHEACHECHEK2 | |
| SCHEMBL20765497 | 0.72 | MGLL (0.58) | MGLLBCHEACHECHEK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | disclosed |