Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 10/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986737 | 0.92 | ACACB (0.51) | MGLLCHEK2BCHEACHEACACB | |
| SCHEMBL19986696 | 0.88 | ACACB (0.51) | MGLLCHEK2ACACBHPGD | |
| SCHEMBL19970784 | 0.85 | MGLL (0.59) | MGLLCHEK2BCHEACHEACACB | |
| SCHEMBL21843704 | 0.79 | HPGD (0.70) | MGLLCHEK2ACACBACACAHPGD | |
| SCHEMBL16619560 | 0.78 | MGLL (0.65) | MGLLCHEK2ACACBACACAHPGD | |
| SCHEMBL19970809 | 0.78 | ACACB (0.52) | MGLLCHEK2BCHEACHEACACB | |
| SCHEMBL19970783 | 0.78 | ENPP2 (0.56) | MGLLCHEK2ACACBHPGD | |
| SCHEMBL20765523 | 0.75 | MGLL (0.58) | MGLLCHEK2BCHEACHEACACB | |
| SCHEMBL20765482 | 0.75 | MGLL (0.56) | MGLLCHEK2BCHEACHEHPGD | |
| SCHEMBL20765786 | 0.75 | BCHE (0.55) | MGLLCHEK2BCHEACHEACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |