Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765557 | 0.85 | L3MBTL1 (0.58) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL20765762 | 0.85 | L3MBTL1 (0.62) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL12431599 | 0.84 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL12431600 | 0.82 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL5805385 | 0.81 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL1965011 | 0.79 | KMT2A (0.65) | ALDH1A1SMN1; SMN2KDM4EPOLBTDP1 | |
| SCHEMBL30447626 | 0.79 | KMT2A (0.65) | ALDH1A1SMN1; SMN2KDM4EPOLBTDP1 | |
| SCHEMBL14091323 | 0.79 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL20765543 | 0.77 | SMN1; SMN2 (0.79) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL15445064 | 0.77 | NPSR1 (0.67) | ALDH1A1KDM4EPOLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |