Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13150118 | 0.85 | KMT2A (0.63) | FAAHMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL20765500 | 0.83 | MAPK14 (0.70) | MAPK14TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL3752475 | 0.82 | FAAH (0.70) | FAAHMAPK14TSHRNPC1ENPP2 | |
| SCHEMBL18935537 | 0.80 | FAAH (0.58) | FAAHMAPK14TSHR | |
| SCHEMBL19970835 | 0.79 | BCHE (0.53) | TNKSPARP1TNKS2PARP2GRIN2B | |
| SCHEMBL29132085 | 0.79 | SIGMAR1 (0.59) | FAAHMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL3597986 | 0.79 | FAAH (1.00) | FAAH | |
| SCHEMBL23301159 | 0.78 | KDM4E (0.65) | FAAHTSHRMEN1KMT2ANPSR1 | |
| SCHEMBL29943050 | 0.78 | KDM4E (0.65) | FAAHTSHRMEN1KMT2ANPSR1 | |
| SCHEMBL20782366 | 0.78 | MAPK14 (0.71) | MAPK14MEN1KMT2ANPSR1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |