Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290573 | 0.83 | MEN1 (0.64) | LMNAPOLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL13290560 | 0.82 | KMT2A (0.47) | MAPTSMN1; SMN2POLBNPC1KMT2A | |
| SCHEMBL8262960 | 0.82 | MEN1 (0.60) | MAPTPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL20765609 | 0.81 | HSD11B1 (0.41) | MYCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL20765611 | 0.81 | HSD11B1 (0.41) | MYCMAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL13290574 | 0.80 | TLR9 (0.53) | SMN1; SMN2NPC1KMT2AMEN1HPGD | |
| SCHEMBL8262965 | 0.79 | ACACB (0.48) | KMT2AMEN1 | |
| SCHEMBL16598917 | 0.79 | MAOB (0.56) | MAPTSMN1; SMN2LMNAKMT2AL3MBTL1 | |
| SCHEMBL8264513 | 0.79 | FGFR1 (0.55) | MAPTSMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL13290557 | 0.79 | KMT2A (0.51) | POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |