Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765609 | 1.00 | HSD11B1 (0.41) | HSD11B1MAPTSMN1; SMN2LMNAMYC | |
| SCHEMBL20765646 | 0.81 | MYC (0.53) | MAPTSMN1; SMN2LMNAMYCTRPV1 | |
| SCHEMBL20765458 | 0.79 | BCHE (0.42) | HSD11B1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL20765461 | 0.79 | BCHE (0.42) | HSD11B1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL20765826 | 0.77 | BCHE (0.41) | HSD11B1ALDH1A1POLBKDM4E | |
| SCHEMBL20765824 | 0.77 | BCHE (0.41) | HSD11B1ALDH1A1POLBKDM4E | |
| SCHEMBL20765550 | 0.74 | BRS3 (0.40) | SMN1; SMN2GHSR | |
| SCHEMBL20766168 | 0.74 | HPGD (0.43) | MAPTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL20766167 | 0.74 | HPGD (0.43) | MAPTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL20765584 | 0.69 | HSD11B1 (0.49) | HSD11B1SMN1; SMN2ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038683-A1 | COMPOUNDS TARGETING TANDEM BRCT DOMAINS OF BRCA1, COMPOSITIONS AND METHODS THEREOF | INSTITUTE FOR STEM CELL BIOLOGY AND REGENERATIVE MEDICINE (IN) | 2019-02-28 | — | — | WO | claimed |