Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686924 | 1.00 | BCHE (0.48) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20794526 | 1.00 | BCHE (0.48) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20766029 | 1.00 | BCHE (0.48) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20794834 | 0.87 | ACHE (0.48) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20794833 | 0.87 | ACHE (0.48) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL29283482 | 0.84 | BCHE (0.47) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20766194 | 0.83 | BCHE (0.51) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20765890 | 0.83 | BCHE (0.51) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20766105 | 0.83 | BCHE (0.51) | BCHEACHEBACE1KMT2AMEN1 | |
| SCHEMBL20765867 | 0.83 | BCHE (0.51) | BCHEACHEBACE1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |