Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | RB1 | P06400 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20794834 | 1.00 | ACHE (0.48) | ACHEBACE1BCHENPC1GAA | |
| SCHEMBL20766029 | 0.87 | BCHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL23686924 | 0.87 | BCHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20794526 | 0.87 | BCHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20766012 | 0.87 | BCHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20780641 | 0.83 | ACHE (0.51) | ACHEBACE1BCHEOPRK1RB1 | |
| SCHEMBL20780642 | 0.83 | ACHE (0.51) | ACHEBACE1BCHEOPRK1RB1 | |
| SCHEMBL4206550 | 0.78 | ACHE (0.58) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL12380 | 0.76 | ACHE (0.48) | ACHEBACE1BCHENPC1GAA | |
| SCHEMBL17185176 | 0.75 | ACHE (0.55) | ACHEBACE1BCHERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |