Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779639 | 0.89 | MMP1 (0.44) | MMP1KIF11AKR1C3AKR1C2AR | |
| SCHEMBL20779642 | 0.78 | TEAD1 (0.56) | KIF11ALDH1A1AKR1C3AKR1C2PLA2G7 | |
| SCHEMBL30410558 | 0.78 | TEAD1 (0.56) | KIF11ALDH1A1AKR1C3AKR1C2PLA2G7 | |
| SCHEMBL20552520 | 0.72 | KIF11 (0.45) | KDM4EKIF11ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL20552318 | 0.71 | LRRK2 (0.50) | KDM4EKIF11ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL21091532 | 0.71 | AKR1C3 (0.50) | KDM4EKIF11AKR1C3AKR1C2TAS2R14 | |
| SCHEMBL29074795 | 0.70 | BCL6 (0.59) | KDM4EKIF11ALDH1A1FBP1 | |
| SCHEMBL20767101 | 0.70 | KIF11 (0.45) | KDM4EKIF11ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL20553084 | 0.70 | SLC22A12 (0.47) | KDM4EKIF11ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL20552788 | 0.70 | LRRK2 (0.49) | KDM4EKIF11ALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691623-A1 | BENZOSULFONYL COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |