Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 8/20 | 0.65 |
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | CA1 | P00915 | 7/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766620 | 0.81 | CA2 (0.62) | PTGES2CA2CA1CA12CA9 | |
| SCHEMBL1921457 | 0.79 | ALDH1A1 (0.55) | KIF11MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL3777574 | 0.79 | PTGES2 (1.00) | PTGES2CA2CA1CA9MAPT | |
| SCHEMBL30194891 | 0.79 | PTGES2 (0.54) | PTGES2CA2CA1CA12CA9 | |
| SCHEMBL25042639 | 0.75 | SMN1; SMN2 (0.51) | KIF11MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL20766416 | 0.75 | CA2 (0.71) | CA2CA1CA12CA9CA7 | |
| SCHEMBL30482561 | 0.75 | SMN1; SMN2 (0.51) | KIF11MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL15875869 | 0.75 | MAPT (0.68) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL29824523 | 0.75 | MAPT (0.68) | MAPTKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL3774801 | 0.74 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691623-A1 | BENZOSULFONYL COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |