Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SDCBP | O00560 | 2/20 | 0.36 |
| ▸ | SDC2 | P34741 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TNF | P01375 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766605 | 1.00 | ALOX15 (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL2250406 | 0.88 | MEN1 (0.48) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL7679763 | 0.87 | ALOX15 (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL7680330 | 0.86 | MAPT (0.44) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL20766677 | 0.85 | NPC1 (0.48) | ALOX15MAPTSMN1; SMN2KDM4ECRBN | |
| SCHEMBL20766676 | 0.85 | NPC1 (0.48) | ALOX15MAPTSMN1; SMN2KDM4ECRBN | |
| SCHEMBL7679480 | 0.85 | ALOX15 (0.43) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL7671077 | 0.84 | ALOX15 (0.43) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 | |
| SCHEMBL28403557 | 0.83 | TNF (0.46) | ALOX15MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7674304 | 0.83 | MAPT (0.42) | ALOX15MAPTSMN1; SMN2KDM4ESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | BIOTHERYX, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. | 2020-07-23 | — | — | US | disclosed |
| EP-3672955-A1 | ETHER COMPOUNDS AND USES THEREOF | Biotheryx Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-111247138-A | Ether compound and use thereof | 拜欧赛里克斯公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019040274-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | EPCAM, ICAM1, SELE | ALOX15 421/4885MAPT 2110/4885SMN1; SMN2 1151/4885 |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | EPCAM, ICAM1, SELE | ALOX15 421/4885MAPT 2110/4885SMN1; SMN2 1151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.