Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30313214 | 1.00 | GAA (0.41) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30313215 | 1.00 | GAA (0.41) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20766901 | 0.84 | GAA (0.36) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2427915 | 0.81 | GAA (0.49) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2249834 | 0.80 | SMN1; SMN2 (0.38) | GAAALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL20766672 | 0.73 | GAA (0.47) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12553220 | 0.73 | DRD2 (0.37) | GAAALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL31184685 | 0.73 | DRD2 (0.37) | GAAALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL31305200 | 0.72 | HPGD (0.46) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3280072 | 0.72 | GAA (0.46) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | BIOTHERYX, INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. | 2020-07-23 | — | — | US | disclosed |
| EP-3672955-A1 | ETHER COMPOUNDS AND USES THEREOF | Biotheryx Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-111247138-A | Ether compound and use thereof | 拜欧赛里克斯公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019040274-A1 | ETHER COMPOUNDS AND USES THEREOF | BIOTHERYX, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927104-B2 | Ether compounds and uses thereof | EPCAM, ICAM1, SELE | GAA 3110/4885ALDH1A1 1945/4885CYP1A2 3444/4885 |
| US-20200231582-A1 | ETHER COMPOUNDS AND USES THEREOF | EPCAM, ICAM1, SELE | GAA 3110/4885ALDH1A1 1945/4885CYP1A2 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.