SCHEMBL20766745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20766638	0.87	MAPT (0.52)	NFKB1BLMPMP22GAAACHE
	SCHEMBL20767168	0.86	GAA (0.40)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL28870476	0.80	MAPT (0.61)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL20563424	0.77	TSHR (0.65)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL1596291	0.75	TSHR (0.62)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL20783618	0.75	CYP2D6 (0.41)	CYP3A4
	SCHEMBL20767011	0.74	TAAR1 (0.42)	NFKB1TSHRCYP3A4GAAPTGS1
	SCHEMBL1595318	0.72	BCHE (0.64)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL1594982	0.72	BCHE (0.64)	NFKB1BLMPMP22TSHRCYP3A4
	SCHEMBL31516847	0.72	TSHR (0.59)	NFKB1BLMPMP22TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.