SCHEMBL20766974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20766196	0.89	BRD4 (0.56)	BRD4YAP1IRAK1IRAK4SYK
	SCHEMBL29901813	0.89	BRD4 (0.56)	BRD4YAP1IRAK1IRAK4SYK
	SCHEMBL20767361	0.85	BRD4 (0.43)	BRD4ALOX15YAP1TEAD1LMNA
	SCHEMBL20766526	0.83	YAP1 (0.57)	BRD4ALOX15YAP1TEAD1LMNA
	SCHEMBL30410106	0.82	BRD4 (0.43)	BRD4ALOX15YAP1LMNAALDH1A1
	SCHEMBL20766518	0.82	BRD4 (0.43)	BRD4ALOX15YAP1LMNAALDH1A1
	SCHEMBL20766210	0.81	BRD4 (0.41)	BRD4ALOX15YAP1LMNAALDH1A1
	SCHEMBL20766351	0.80	GPR39 (0.47)	BRD4ALOX15YAP1LMNAALDH1A1
	SCHEMBL30411184	0.80	GPR39 (0.47)	BRD4ALOX15YAP1LMNAALDH1A1
	SCHEMBL20767153	0.80	YAP1 (0.43)	BRD4ALOX15YAP1TEAD1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.