Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767964 | 0.84 | SCN4A (0.46) | SCN4ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8512161 | 0.82 | ALDH1A1 (0.47) | SCN4ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20767872 | 0.82 | SCN4A (0.48) | SCN4ASCN9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL20767920 | 0.77 | SMN1; SMN2 (0.76) | SCN4ASCN9ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL232915 | 0.75 | RAB9A (0.67) | SCN4ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20767897 | 0.74 | KDM4E (0.53) | NAAASCN4ASCN9ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL17455087 | 0.74 | RAB9A (0.65) | SCN4ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL26683694 | 0.72 | SCN4A (0.38) | SCN4ASCN9ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30688286 | 0.72 | CRBN (0.43) | SCN4ASCN9ARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL26683685 | 0.72 | CRBN (0.43) | SCN4ASCN9ARAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | Wu, Xiao Hua (US) | 2019-03-05 | — | — | US | disclosed |
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | Wu, Xiao Hua (US) | 2019-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221168-B1 | Small-compound enhancers for functional O-mannosylation of alpha-dystroglycan, and uses thereof | MAN2A1, MAN1B1, ALG1 | NAAA 3046/4885SCN4A 1286/4885SCN9A 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.