Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lazabemide SCHEMBL121998 | 1.00 | MAOB (1.00) | MAOBCYP1A2TSHRNFKB1MEN1 | |
| Lazabemide SCHEMBL29710899 | 1.00 | MAOB (1.00) | MAOBCYP1A2TSHRNFKB1MEN1 | |
| Lazabemide SCHEMBL29389663 | 0.98 | MAOB (0.97) | MAOBCYP1A2TSHRNFKB1MEN1 | |
| Lazabemide SCHEMBL1230476 | 0.98 | MAOB (0.97) | MAOBCYP1A2TSHRNFKB1MEN1 | |
| SCHEMBL8973342 | 0.90 | MAOB (0.81) | MAOBMEN1KMT2AEGLN1MAOA | |
| SCHEMBL19835607 | 0.86 | MAOB (0.76) | MAOBMALT1EGLN1MAOANPC1 | |
| SCHEMBL8396789 | 0.83 | MAOB (0.71) | MAOBKMT2AEGLN1MAOANPC1 | |
| SCHEMBL29459609 | 0.83 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL14329887 | 0.83 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL29262574 | 0.83 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |