Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262574 | 1.00 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL8973342 | 0.90 | MAOB (0.81) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL19835607 | 0.86 | MAOB (0.76) | MAOBEGLN1MAOANPC1RAB9A | |
| Lazabemide SCHEMBL29710899 | 0.83 | MAOB (1.00) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL14329887 | 0.83 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL8396789 | 0.83 | MAOB (0.71) | MAOBEGLN1MAOANPC1RAB9A | |
| Lazabemide SCHEMBL121998 | 0.83 | MAOB (1.00) | MAOBEGLN1MAOANPC1RAB9A | |
| Lazabemide SCHEMBL20769840 | 0.83 | MAOB (1.00) | MAOBEGLN1MAOANPC1RAB9A | |
| SCHEMBL16887934 | 0.82 | MAOB (0.69) | MAOBEGLN1MAOANPC1RAB9A | |
| Lazabemide SCHEMBL1230476 | 0.82 | MAOB (0.97) | MAOBEGLN1MAOANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239886-A | Morabamine compound and preparation method and application thereof | 重庆师范大学 | 2024-06-25 | — | — | CN | claimed |
| CN-118239886-A | Morabamine compound and preparation method and application thereof | 重庆师范大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239886-A | Morabamine compound and preparation method and application thereof | 重庆师范大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-109422675-B | Synthesis method of novel monoamine oxidase inhibitor molabemide | 重庆师范大学 | 2022-03-08 | — | — | CN | disclosed |