Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.66 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.66 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.66 |
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986588 | 0.82 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL6825869 | 0.80 | CSNK1A1 (1.00) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL2943452 | 0.80 | GRM5 (0.54) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL4564863 | 0.79 | CSNK1A1 (0.61) | CSNK1A1TYRO3DYRK1BPARP1NUDT1 | |
| Water SCHEMBL30473073 | 0.79 | CSNK1A1 (0.97) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL997865 | 0.78 | GRM5 (0.64) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL29506339 | 0.78 | GRM5 (0.64) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL31249988 | 0.78 | GRM5 (0.64) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL31249984 | 0.78 | GRM5 (0.64) | CSNK1A1TYRO3DYRK1BPARP1GRM5 | |
| SCHEMBL986590 | 0.78 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BPARP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046303-A1 | A METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-03-07 | — | — | WO | disclosed |