Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26116056 | 0.76 | DAO (0.49) | SELEVCAM1 | |
| SCHEMBL30587276 | 0.76 | DAO (0.49) | SELEVCAM1 | |
| SCHEMBL26115151 | 0.74 | HDAC3 (0.36) | — | |
| SCHEMBL30587256 | 0.73 | CSNK2A2 (0.46) | SELEVCAM1 | |
| SCHEMBL26116037 | 0.73 | CSNK2A2 (0.46) | SELEVCAM1 | |
| SCHEMBL20775013 | 0.71 | ALDH1A1 (0.41) | — | |
| SCHEMBL6684473 | 0.69 | DYRK1A (0.44) | AXLPRKCI | |
| SCHEMBL24810237 | 0.64 | ALDH1A1 (0.35) | AXLPRKCI | |
| SCHEMBL30848789 | 0.64 | ALDH1A1 (0.35) | AXLPRKCI | |
| SCHEMBL4350131 | 0.63 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675856-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |