SCHEMBL20774178

SCHEMBL20774178

OCCOc1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1-c1c(OCCO)ccc2cc(-c3cccc4c3sc3ccccc34)ccc12

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
MCL1 Q07820 2/20 0.38
PRKDC P78527 1/20 0.38
S1PR5 Q9H228 10/20 0.37
S1PR4 O95977 7/20 0.37
IDO1 P14902 1/20 0.36
PARP14 Q460N5 1/20 0.36
PTPN1 P18031 1/20 0.34
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575224 1.00 ALOX5 (0.51) ALOX5MCL1PRKDCS1PR5S1PR4
SCHEMBL31443148 0.97 ALOX5 (0.48) ALOX5MCL1PRKDCS1PR5S1PR4
SCHEMBL22080408 0.83 ALOX5 (0.41) ALOX5MCL1PRKDCS1PR5S1PR4
SCHEMBL30873989 0.83 ALOX5 (0.47) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL30874119 0.83 ALOX5 (0.47) ALOX5PRKDCS1PR5S1PR4PARP14
SCHEMBL30874007 0.82 ALOX5 (0.48) ALOX5MCL1PRKDCS1PR5S1PR4
SCHEMBL20774244 0.82 ALOX5 (0.45) ALOX5MCL1IDO1GPR84
SCHEMBL29631695 0.82 ALOX5 (0.45) ALOX5MCL1IDO1GPR84
SCHEMBL30634846 0.82 ALOX5 (0.45) ALOX5MCL1IDO1GPR84
SCHEMBL20774174 0.82 PTPN1 (0.46) ALOX5S1PR5S1PR4PARP14PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676239-B1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPBAU E K (DE) 2026-04-15 EP claimed
US-11072573-B2 Binaphthyl compounds REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2021-07-27 US claimed
US-20200354299-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2020-11-12 US claimed
EP-3676239-A1 BINAPHTHYL COMPOUNDS Reuter Chemische Apparatenbau e.K. (DE) 2020-07-08 EP claimed
WO-2019043060-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU KG (DE) 2019-03-07 WO claimed
EP-3676239-B1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPBAU E K (DE) 2026-04-15 EP disclosed
US-12540215-B2 Method of manufacturing crystalline and amorphous forms of 6,6′-diphenyl-2,2′-bis(2-hydroxyethoxy)-1,1′-binaphthyl and thermoplastic resin therefrom MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-02-03 US disclosed
US-12516153-B2 Thermoplastic resin, method for manufacturing same, and optical lens MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-06 US disclosed
US-20250282910-A1 THERMOPLASTIC RESIN, METHOD FOR MANUFACTURING SAME, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-11 US disclosed
US-11952460-B2 Polycarbonate resin, method for producing the same, and optical lens MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-04-09 US disclosed
US-20230333469-A1 FILM FORMING COMPOSITION FOR LITHOGRAPHY, RESIST PATTERN FORMATION METHOD, AND CIRCUIT PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-19 US disclosed
US-20230333469-A1 FILM FORMING COMPOSITION FOR LITHOGRAPHY, RESIST PATTERN FORMATION METHOD, AND CIRCUIT PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-19 US disclosed
US-20200354299-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2020-11-12 US disclosed
US-20200354299-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2020-11-12 US disclosed
EP-3676239-A1 BINAPHTHYL COMPOUNDS Reuter Chemische Apparatenbau e.K. (DE) 2020-07-08 EP disclosed
EP-3677615-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2020-07-08 EP disclosed
US-20200181325-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING THE SAME, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-06-11 US disclosed
US-20200181325-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING THE SAME, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-06-11 US disclosed
WO-2019043060-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU KG (DE) 2019-03-07 WO disclosed
WO-2019043060-A1 BINAPHTHYL COMPOUNDS REUTER CHEMISCHE APPARATEBAU KG (DE) 2019-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282910-A1 THERMOPLASTIC RESIN, METHOD FOR MANUFACTURING SAME, AND OPTICAL LENS UFL1, RAD51, RPS27L ALOX5 1537/4885MCL1 2686/4885PRKDC 2855/4885
US-20200354299-A1 BINAPHTHYL COMPOUNDS UACA, C9, C1S ALOX5 164/4885MCL1 3810/4885PRKDC 3984/4885
US-12540215-B2 Method of manufacturing crystalline and amorphous forms of 6,6′-diphenyl-2,2′-bis(2-hydroxyethoxy)-1,1′-binaphthyl and thermoplastic resin therefrom PBRM1, XRCC6, B2M ALOX5 1685/4885MCL1 2953/4885PRKDC 1167/4885
US-11072573-B2 Binaphthyl compounds UACA, C9, C1S ALOX5 164/4885MCL1 3810/4885PRKDC 3984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.