SCHEMBL2077532

SCHEMBL2077532

COc1ccccc1[SiH](Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA14 Q9ULX7 1/20 0.55
ALDH1A1 P00352 5/20 0.44
TP53 P04637 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
ADRA2B P18089 1/20 0.44
PTGS1 P23219 1/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 2/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
IDO1 P14902 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1325474 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL28305734 0.79 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL6433975 0.78 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL3300372 0.76 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL31310648 0.76 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL18492338 0.76 ALDH1A1 (0.50) ALDH1A1TDP1MAPTGAAMAPK1
1,2-Dimethoxybenzene SCHEMBL5308636 0.73 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL105872 0.73 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL29351917 0.73 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL11638262 0.71 CA1 (0.81) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161386-A Binaphthyl hepta-phosphine hetero-monohydrosilane and synthetic method and application thereof 南方科技大学 2024-12-20 CN disclosed
CN-114874251-A Silicon center chiral silanol and synthetic method thereof 南方科技大学 2022-08-09 CN disclosed
US-8163863-B2 Polysilane and polysilane-containing resin composition OSAKA GAS CO., LTD. (JP) 2012-04-24 US disclosed
US-20090156775-A1 POLYSILANE AND POLYSILANE-CONTAINING RESIN COMPOSITION OSAKA GAS CO., LTD. (JP) 2009-06-18 US disclosed
EP-1958979-A1 POLYSILANE AND RESIN COMPOSITION CONTAINING POLYSILANE OSAKA GAS CO., LTD. (JP) 2008-08-20 EP disclosed