SCHEMBL1325474

SCHEMBL1325474

COc1ccccc1[SiH](c1ccccc1OC)c1ccccc1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA7 P43166 2/20 0.60
CA9 Q16790 2/20 0.60
CA12 O43570 1/20 0.60
CA4 P22748 1/20 0.60
CA14 Q9ULX7 1/20 0.60
ALDH1A1 P00352 6/20 0.48
TP53 P04637 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
ADRA2B P18089 1/20 0.48
PTGS1 P23219 1/20 0.48
MAPK1 P28482 2/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ENPP2 Q13822 1/20 0.44
ORAI1 Q96D31 1/20 0.43
ORAI2 Q96SN7 1/20 0.43
ORAI3 Q9BRQ5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27949719 0.86 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL6433975 0.82 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL31310648 0.80 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL2077532 0.80 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL3300372 0.80 CA1 (0.55) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL5308636 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL29351917 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL105872 0.76 CA1 (1.00) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL9793057 0.74 CA1 (0.93) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL28602492 0.74 CA1 (0.93) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10211412-B2 Charge-transporting varnish, charge-transporting thin film and method for manufacturing same, and organic electroluminescent element and method for manufacturing same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-02-19 US disclosed
EP-3168889-B1 CHARGE-TRANSPORTING VARNISH, CHARGE-TRANSPORTING THIN FILM AND METHOD FOR MANUFACTURING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NISSAN CHEMICAL IND LTD (JP) 2018-09-12 EP disclosed
US-20170155060-A1 CHARGE-TRANSPORTING VARNISH, CHARGE-TRANSPORTING THIN FILM AND METHOD FOR MANUFACTURING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-06-01 US disclosed
EP-3168889-A1 CHARGE-TRANSPORTING VARNISH, CHARGE-TRANSPORTING THIN FILM AND METHOD FOR MANUFACTURING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME Nissan Chemical Industries, Ltd. (JP) 2017-05-17 EP disclosed
US-9206202-B2 Carbazole derivative and semiconductor nanocrystal RICOH COMPANY, LTD. (JP) 2015-12-08 US disclosed
US-8747700-B2 Charge-transporting varnishes NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-10 US disclosed
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL RICOH COMPANY, LTD. (JP) 2013-01-31 US disclosed
US-8058261-B2 3′-ethynylcytidine derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 2011-11-15 US disclosed
EP-2045258-B1 3'-ETHYNYLCYTIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 2011-09-21 EP disclosed
US-20110195355-A1 CHARGE-TRANSPORTING VARNISHES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-11 US disclosed
EP-2339659-A1 CHARGE-TRANSPORTING VARNISHES Nissan Chemical Industries, Ltd. (JP) 2011-06-29 EP disclosed
US-7825103-B2 5'-O-triisopropylsilyl-2'-cyano-2'-deoxy-1- beta -D-arabinofuranosylcytosine; antitumor agents TAIHO PHARMACEUTICAL CO., LTD. (JP) 2010-11-02 US disclosed
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Sasaki, Takuma (JP) 2009-12-10 US disclosed
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2009-05-07 US disclosed
EP-2045258-A1 3'-ETHYNYLCYTIDINE DERIVATIVE Taiho Pharmaceutical Co., Ltd. (JP) 2009-04-08 EP disclosed
EP-1845102-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 2007-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL NAT1, AHR, ARSA CA1 2989/4885CA2 1970/4885CA7 2274/4885
US-10211412-B2 Charge-transporting varnish, charge-transporting thin film and method for manufacturing same, and organic electroluminescent element and method for manufacturing same SLCO4C1, SLC43A1, SLC18A2 CA1 1418/4885CA2 488/4885CA7 591/4885
US-20090118222-A1 NOVEL PYRIMIDINE NUCLEOSIDE COMPOUND OR ITS SALT CDK10, SRSF9, SNRPD1 CA1 1686/4885CA2 1991/4885CA7 1853/4885
US-20090306008-A1 3'-ETHYNYLCYTIDINE DERIVATIVE SLC7A1, SLC29A1, SLC26A3 CA1 2058/4885CA2 946/4885CA7 376/4885
US-20170155060-A1 CHARGE-TRANSPORTING VARNISH, CHARGE-TRANSPORTING THIN FILM AND METHOD FOR MANUFACTURING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME SLCO4C1, SLC43A1, SLC18A2 CA1 1418/4885CA2 488/4885CA7 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.