Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 14/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782934 | 0.84 | NLRP3 (0.74) | NLRP3ACP1 | |
| SCHEMBL20783123 | 0.81 | NLRP3 (0.65) | NLRP3ACP1 | |
| SCHEMBL20775419 | 0.79 | NLRP3 (1.00) | NLRP3 | |
| SCHEMBL20775422 | 0.74 | NLRP3 (0.61) | NLRP3HPGDKDM4E | |
| SCHEMBL20782977 | 0.73 | NLRP3 (0.59) | NLRP3 | |
| SCHEMBL20783097 | 0.72 | NLRP3 (1.00) | NLRP3 | |
| SCHEMBL20782915 | 0.69 | NLRP3 (0.55) | NLRP3ACP1 | |
| SCHEMBL20783076 | 0.67 | NLRP3 (0.53) | NLRP3KDM4E | |
| SCHEMBL4264655 | 0.61 | AVPR2 (0.52) | NLRP3HPGD | |
| SCHEMBL4264663 | 0.61 | AVPR2 (0.52) | NLRP3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043610-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |