Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782934 | 0.79 | NLRP3 (0.74) | NLRP3 | |
| SCHEMBL20782915 | 0.77 | NLRP3 (0.55) | NLRP3RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20775419 | 0.76 | NLRP3 (1.00) | NLRP3 | |
| SCHEMBL20783123 | 0.74 | NLRP3 (0.65) | NLRP3RAB9ANPC1 | |
| SCHEMBL20782977 | 0.74 | NLRP3 (0.59) | NLRP3SMN1; SMN2 | |
| SCHEMBL20775414 | 0.74 | NLRP3 (0.65) | NLRP3KDM4EHPGD | |
| SCHEMBL20783097 | 0.74 | NLRP3 (1.00) | NLRP3 | |
| SCHEMBL20783076 | 0.73 | NLRP3 (0.53) | NLRP3MEN1KMT2AMAPK1POLB | |
| SCHEMBL20188746 | 0.70 | GRM4 (0.52) | RAB9ANPC1ADRB2MEN1KMT2A | |
| SCHEMBL20207639 | 0.65 | GAA (0.41) | RAB9ANPC1ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043610-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019043610-A1 | NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |