Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.35 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779647 | 0.79 | KDM1A (0.52) | KDM1AGPR35GRIK1GRIA2KMT2A | |
| SCHEMBL20779509 | 0.77 | KDM1A (0.52) | KDM1AGPR35GRIK1GRIA2MEN1 | |
| SCHEMBL20766338 | 0.75 | KDM1A (0.50) | KDM1AGPR35GRIK1GRIA2MEN1 | |
| SCHEMBL25788936 | 0.73 | KDM1A (0.46) | KDM1AGPR35GRIK1GRIA2 | |
| SCHEMBL20779736 | 0.71 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL22646195 | 0.69 | YAP1 (0.43) | KMT2AALDH1A1 | |
| SCHEMBL30734275 | 0.66 | TDP1 (0.41) | GPR35GRIK1GRIA2MEN1KMT2A | |
| SCHEMBL20779612 | 0.66 | BRD4 (0.43) | KDM1AGPR35GRIK1GRIA2 | |
| SCHEMBL20766229 | 0.65 | KDM1A (0.43) | KDM1AGPR35GRIK1GRIA2 | |
| SCHEMBL27276191 | 0.65 | MAPT (0.49) | GPR35GRIK1GRIA2STSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |