Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766300 | 0.81 | TEAD1 (0.53) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL20766837 | 0.80 | TEAD1 (0.54) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL20767220 | 0.77 | TEAD1 (0.49) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL20779892 | 0.77 | TEAD1 (0.62) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL22635632 | 0.76 | TEAD1 (0.48) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL22635666 | 0.73 | ALDH1A1 (0.58) | TEAD1YAP1TNNI3KMAPK1MEN1 | |
| SCHEMBL20779642 | 0.73 | TEAD1 (0.56) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL30410558 | 0.73 | TEAD1 (0.56) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL22719765 | 0.73 | TEAD1 (0.56) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 | |
| SCHEMBL29504945 | 0.73 | TEAD1 (0.56) | TEAD1YAP1TNNI3KAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |