⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417047 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL172644 | 0.78 | LMNA (0.39) | — | |
| SCHEMBL21739998 | 0.75 | TP53 (0.37) | — | |
| SCHEMBL7777047 | 0.75 | LMNA (0.38) | — | |
| SCHEMBL18869460 | 0.73 | TP53 (0.35) | — | |
| SCHEMBL22794016 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL26205525 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL4149586 | 0.70 | — | — | |
| SCHEMBL24332028 | 0.70 | SLC6A4 (0.32) | — | |
| SCHEMBL12533456 | 0.69 | TP53 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030814-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2020-02-13 | — | — | WO | disclosed |
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |