Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417047 | 1.00 | LMNA (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL13996004 | 0.86 | ALDH1A1 (0.33) | — | |
| SCHEMBL7777047 | 0.86 | LMNA (0.38) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL172646 | 0.81 | LMNA (0.40) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL22751916 | 0.79 | LMNA (0.44) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL20780307 | 0.78 | — | — | |
| SCHEMBL24138226 | 0.77 | LMNA (0.61) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7965035 | 0.77 | LMNA (0.37) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7114924 | 0.77 | LMNA (0.42) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7864361 | 0.77 | LMNA (0.42) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |