Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527263 | 0.82 | CES2 (0.33) | CCR2CES2ADRB1MAPTRAPGEF4 | |
| SCHEMBL15693716 | 0.71 | CES2 (0.38) | CCR2CES2ADRB1MAPTRAPGEF4 | |
| SCHEMBL15693717 | 0.71 | KDM1A (0.41) | CCR2CES2ADRB1KDM1ARCOR1 | |
| SCHEMBL21020525 | 0.69 | CES2 (0.34) | CCR2CES2 | |
| SCHEMBL30527262 | 0.68 | KDM1A (0.33) | IDO1KDM1ARCOR1 | |
| SCHEMBL15693712 | 0.68 | KDM1A (0.38) | CCR2CES2ADRB1MAPTRAPGEF4 | |
| SCHEMBL440959 | 0.68 | CES2 (0.58) | CES2ADRB1MAPTRAPGEF4IDO1 | |
| SCHEMBL20076511 | 0.68 | ITGB3 (0.34) | CES2 | |
| SCHEMBL19102566 | 0.67 | NOTUM (0.37) | CCR2CES2ADRB1KDM1A | |
| SCHEMBL17151050 | 0.67 | NOTUM (0.37) | CCR2CES2ADRB1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |