Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 6/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780432 | 0.91 | CETP (0.45) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL20794455 | 0.86 | CETP (0.41) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL15744001 | 0.84 | CETP (0.37) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL13395500 | 0.82 | CETP (0.36) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL20780482 | 0.82 | HTR1A (0.56) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL20780487 | 0.81 | CETP (0.40) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL14214515 | 0.81 | CETP (0.43) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL13950177 | 0.80 | CETP (0.42) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL23846735 | 0.74 | CETP (0.42) | CETPHTR2BCHRM2HTR1ADRD3 | |
| SCHEMBL20794457 | 0.74 | CETP (0.42) | CETPHTR2BCHRM2HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |