Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744001 | 0.83 | CETP (0.37) | CETPNOTUMARCHRM2HTR1A | |
| SCHEMBL13395500 | 0.81 | CETP (0.36) | CETPNOTUMARCHRM2HTR1A | |
| SCHEMBL13547541 | 0.81 | HTR1A (0.47) | CETPCHRM2HTR1ADRD3HTR2B | |
| SCHEMBL20780485 | 0.81 | CETP (0.40) | CETPNOTUMCHRM2HTR1ADRD3 | |
| SCHEMBL13413436 | 0.80 | CETP (0.44) | CETPFADS1SMN1; SMN2 | |
| SCHEMBL23846735 | 0.73 | CETP (0.42) | CETPCHRM2HTR1ADRD3HTR2B | |
| SCHEMBL20794457 | 0.73 | CETP (0.42) | CETPCHRM2HTR1ADRD3HTR2B | |
| SCHEMBL20780432 | 0.70 | CETP (0.45) | CETPCHRM2HTR1ADRD3HTR2B | |
| SCHEMBL13547542 | 0.70 | HTR2C (0.40) | ARHTR2B | |
| SCHEMBL7786047 | 0.70 | HTR1A (0.39) | NOTUMCHRM2HTR1ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119476-A1 | Cetp Inhibitors | ALI AMJAD | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119476-A1 | Cetp Inhibitors | CETP, APOB, MTTP | CETP 1/4885NOTUM 160/4885FADS1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.