Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | RB1 | P06400 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780642 | 1.00 | ACHE (0.51) | ACHEBACE1BCHEFABP6ALDH1A1 | |
| SCHEMBL4206550 | 0.87 | ACHE (0.58) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20765890 | 0.86 | BCHE (0.51) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20765867 | 0.86 | BCHE (0.51) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20766139 | 0.86 | BCHE (0.51) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20766105 | 0.86 | BCHE (0.51) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20766194 | 0.86 | BCHE (0.51) | ACHEBACE1BCHEFABP6HRH3 | |
| SCHEMBL20794833 | 0.83 | ACHE (0.48) | ACHEBACE1BCHEALDH1A1OPRK1 | |
| SCHEMBL20794834 | 0.83 | ACHE (0.48) | ACHEBACE1BCHEALDH1A1OPRK1 | |
| SCHEMBL23686826 | 0.82 | BCHE (0.50) | ACHEBACE1BCHEHRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |