⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689188 | 0.94 | — | — | |
| SCHEMBL28317576 | 0.94 | — | — | |
| SCHEMBL486442 | 0.92 | DPP7 (0.47) | — | |
| SCHEMBL2004703 | 0.88 | — | — | |
| SCHEMBL268866 | 0.88 | DPP7 (0.32) | — | |
| SCHEMBL22711077 | 0.84 | DPP7 (0.33) | — | |
| SCHEMBL2850218 | 0.79 | CHRM2 (0.34) | — | |
| SCHEMBL27646786 | 0.79 | GNAI3 (0.34) | — | |
| SCHEMBL14013510 | 0.77 | GAA (0.35) | — | |
| SCHEMBL181625 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |
| CN-112094273-A | Synthetic method of bicyclic guanidine | 天津全和诚科技有限责任公司 | 2020-12-18 | — | — | CN | disclosed |
| US-10222050-B2 | Lighting device | KABUSHIKI KAISHA TOSHIBA (JP) | 2019-03-05 | — | — | US | disclosed |