Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 10/20 | 0.49 |
| ▸ | LOX | P28300 | 8/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24261152 | 0.87 | LOXL2 (0.51) | LOXL2LOXRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL12093687 | 0.83 | LOXL2 (0.65) | LOXL2LOXNR3C2 | |
| SCHEMBL20784555 | 0.80 | LOXL2 (0.48) | LOXL2LOXRAB9AL3MBTL1NPC1 | |
| SCHEMBL17393176 | 0.74 | CLK4 (0.54) | NR3C2RAB9AIGF1RNPC1 | |
| SCHEMBL16453534 | 0.72 | LOXL2 (0.71) | LOXL2LOXRAB9AL3MBTL1NPC1 | |
| SCHEMBL19159805 | 0.72 | PDE2A (0.48) | LOXL2LOXRAB9ANPC1 | |
| SCHEMBL91277 | 0.71 | TAAR1 (0.64) | — | |
| SCHEMBL19492384 | 0.71 | LOX (0.57) | LOXL2LOX | |
| SCHEMBL3196793 | 0.71 | TTR (0.54) | ALDH1A1NPC1HTT | |
| SCHEMBL28655990 | 0.71 | LOXL2 (0.55) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |