Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23866826 | 0.89 | MEN1 (0.35) | NPC1RAB9APLA2G1BATG4BMEN1 | |
| SCHEMBL2251395 | 0.87 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL2248688 | 0.87 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL29388571 | 0.87 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL29471925 | 0.87 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL17347665 | 0.87 | MEN1 (0.36) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL19532862 | 0.86 | NPC1 (0.34) | NPC1RAB9AMEN1KMT2AALOX15 | |
| SCHEMBL19603302 | 0.85 | ALOX15 (0.34) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL19603297 | 0.85 | ALDH1A1 (0.40) | NPC1RAB9AMEN1KMT2AALOX15 | |
| SCHEMBL2250757 | 0.85 | ALDH1A1 (0.40) | NPC1RAB9AMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040109-A1 | PROCESSES FOR PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION (US) | 2019-02-28 | — | — | WO | disclosed |