Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976137 | 1.00 | PPARG (0.44) | PPARGPPARADPP4DPP7TAAR1 | |
| SCHEMBL976138 | 1.00 | PPARG (0.44) | PPARGPPARADPP4DPP7TAAR1 | |
| SCHEMBL3323726 | 0.83 | CA12 (0.40) | PPARGPPARADPP4DPP7DPP8 | |
| SCHEMBL978947 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL29478389 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL288805 | 0.81 | DPP4 (0.41) | DPP4DPP7CPA1GABBR2GABBR1 | |
| SCHEMBL29478405 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5079144 | 0.81 | AKR1B1 (0.55) | DPP4DPP7TAAR1CPA1GABBR2 | |
| SCHEMBL288309 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL978945 | 0.81 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| US-20190076400-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076400-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | OPRL1, OPRM1, OPRK1 | PPARG 1269/4885PPARA 539/4885DPP4 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.