Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12622104 | 0.87 | POLB (0.55) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL22381075 | 0.85 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12623988 | 0.84 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12673214 | 0.84 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12624222 | 0.84 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12623932 | 0.83 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12627182 | 0.81 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12626263 | 0.81 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HCRTR1HCRTR2POLB | |
| SCHEMBL12627122 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL12623952 | 0.81 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222368-B2 | Alzheimer's disease assay in a living patient | PAIN THERAPEUTICS, INC. (US) | 2019-03-05 | — | — | US | disclosed |