Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870006 | 0.90 | CTSL (0.51) | CTSL | |
| SCHEMBL21627147 | 0.90 | CTSL (0.51) | CTSL | |
| SCHEMBL24012348 | 0.86 | PSMB8 (0.53) | CTSL | |
| SCHEMBL16870000 | 0.86 | PSMB8 (0.53) | CTSL | |
| SCHEMBL18840120 | 0.86 | CTSL (0.52) | CTSLPTGER4SIRT2 | |
| SCHEMBL21627021 | 0.84 | CTSL (0.48) | CTSLPTGER4SIRT2 | |
| SCHEMBL16869960 | 0.84 | CTSL (0.48) | CTSLPTGER4SIRT2 | |
| SCHEMBL18258354 | 0.83 | CTSL (0.52) | CTSLPTGER4SIRT2FOLH1CPB1 | |
| SCHEMBL21627096 | 0.82 | CTSL (0.54) | CTSL | |
| SCHEMBL16862485 | 0.82 | CTSL (0.54) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221213-B2 | Pharmaceutically relevant aromatic-cationic peptides | STEALTH BIOTHERAPEUTICS CORP (MC) | 2019-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221213-B2 | Pharmaceutically relevant aromatic-cationic peptides | ADM2, VIP, ANPEP | CTSL 212/4885PTGER4 4881/4885SIRT2 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.