SCHEMBL21627147

SCHEMBL21627147

Cc1cc(OCc2ccccc2)cc(C)c1CC(N)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16870006 1.00 CTSL (0.51) CTSL
SCHEMBL16862485 0.93 CTSL (0.54) CTSL
SCHEMBL21627096 0.93 CTSL (0.54) CTSL
Hydrochloric Acid SCHEMBL16862473 0.92 CTSL (0.53) CTSL
SCHEMBL20794744 0.90 CTSL (0.49) CTSL
SCHEMBL24012348 0.89 PSMB8 (0.53) CTSL
SCHEMBL16870000 0.89 PSMB8 (0.53) CTSL
SCHEMBL18840120 0.89 CTSL (0.52) CTSL
SCHEMBL18840126 0.88 PSMB1 (0.51) —
Trifluoroacetic Acid SCHEMBL16862455 0.88 CTSL (0.51) CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087093-B1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2021-11-10 — — EP disclosed
US-10696716-B2 Pharmaceutically relevant aromatic-cationic peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2020-06-30 — — US disclosed
US-20200024308-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2020-01-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200024308-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES ADM2, VIP, ANPEP CTSL 212/4885
US-10696716-B2 Pharmaceutically relevant aromatic-cationic peptides ADM2, VIP, ANPEP CTSL 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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