Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701565 | 0.86 | TP53 (0.40) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL17207595 | 0.77 | CARM1 (0.43) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL14342364 | 0.75 | CARM1 (0.38) | TP53SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL22294037 | 0.74 | CYP2C19 (0.38) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL20796254 | 0.73 | MEN1 (0.36) | MEN1KMT2AUSP2ALDH1A1CNR1 | |
| SCHEMBL441490 | 0.73 | GBA1 (0.38) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL6487250 | 0.73 | KMT2A (0.33) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL13600648 | 0.72 | MEN1 (0.36) | TP53SMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL17057349 | 0.72 | CARM1 (0.42) | TP53SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19955066 | 0.71 | SMN1; SMN2 (0.46) | TP53SMN1; SMN2KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |