Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17207595 | 0.80 | CARM1 (0.43) | KMT2AMEN1HPGDTP53SMN1; SMN2 | |
| SCHEMBL12465581 | 0.79 | ACE2 (0.48) | KMT2AACE2MEN1CNR1CNR2 | |
| SCHEMBL1307987 | 0.77 | ADH1B (0.38) | KMT2AACE2MEN1HPGDTP53 | |
| SCHEMBL22294037 | 0.77 | CYP2C19 (0.38) | KMT2AACE2MEN1HPGDTP53 | |
| SCHEMBL1307984 | 0.77 | TP53 (0.34) | KMT2AACE2MEN1HPGDTP53 | |
| SCHEMBL14701565 | 0.76 | TP53 (0.40) | KMT2AMEN1HPGDTP53SMN1; SMN2 | |
| SCHEMBL10177623 | 0.75 | CARM1 (0.58) | KMT2AMEN1NPC1ALDH1A1CARM1 | |
| SCHEMBL17057349 | 0.74 | CARM1 (0.42) | KMT2AMEN1HPGDTP53SMN1; SMN2 | |
| SCHEMBL12551015 | 0.74 | ACE2 (0.67) | KMT2AACE2MEN1TP53SMN1; SMN2 | |
| SCHEMBL19955066 | 0.74 | SMN1; SMN2 (0.46) | KMT2ATP53SMN1; SMN2USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939866-B2 | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2005-09-06 | — | — | US | disclosed |