Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARF6 | P62330 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20796519 | 0.92 | ARF6 (0.58) | ARF6MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL20796483 | 0.81 | ARF6 (1.00) | ARF6 | |
| SCHEMBL20796503 | 0.80 | ARF6 (0.67) | ARF6PSD | |
| SCHEMBL20796522 | 0.75 | ARF6 (0.65) | ARF6PSD | |
| SCHEMBL20796214 | 0.75 | ARF6 (0.86) | ARF6 | |
| SCHEMBL20796524 | 0.73 | ARF6 (0.58) | ARF6KDM4EALDH1A1NPC1HTT | |
| SCHEMBL20796643 | 0.73 | ARF6 (0.69) | ARF6PSD | |
| SCHEMBL20796502 | 0.73 | ARF6 (0.66) | ARF6KDM4EALDH1A1NPC1HTT | |
| SCHEMBL20796528 | 0.70 | ARF6 (0.69) | ARF6MAPTHTTMEN1KMT2A | |
| SCHEMBL20796639 | 0.69 | ARF6 (0.67) | ARF6PSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414442-B2 | ARF6 inhibitors and related methods | NAVIGEN, INC. (US) | 2022-08-16 | — | — | US | disclosed |
| US-20210017201-A1 | ARF6 INHIBITORS AND RELATED METHODS | NAVIGEN, INC. | 2021-01-21 | — | — | US | disclosed |
| WO-2019040499-A2 | ARF6 INHIBITORS AND RELATED METHODS | NAVIGEN, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017201-A1 | ARF6 INHIBITORS AND RELATED METHODS | ARF6, ARF1, ARF5 | ARF6 1/4885MAPT 3802/4885TP53 2146/4885 |
| US-11414442-B2 | ARF6 inhibitors and related methods | ARF6, ARF1, ARF5 | ARF6 1/4885MAPT 3802/4885TP53 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.