SCHEMBL20797012

SCHEMBL20797012

CCCC1CCC(C2CCC(O)(c3ccc(C(F)(F)F)c(F)c3F)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 4/20 0.39
OPRM1 P35372 1/20 0.39
OPRK1 P41145 1/20 0.39
TLR4 O00206 1/20 0.32
SOS1 Q07889 1/20 0.31
KCNN4 O15554 1/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20808301 1.00 OPRL1 (0.39) OPRL1OPRM1OPRK1TLR4SOS1
SCHEMBL20808304 1.00 OPRL1 (0.39) OPRL1OPRM1OPRK1TLR4SOS1
SCHEMBL14494616 0.86 OPRL1 (0.36) OPRL1OPRM1OPRK1TLR4CYP2C9
SCHEMBL2909182 0.86 OPRL1 (0.36) OPRL1OPRM1OPRK1TLR4CYP2C9
SCHEMBL2909179 0.86 OPRL1 (0.36) OPRL1OPRM1OPRK1TLR4CYP2C9
SCHEMBL2909177 0.86 OPRL1 (0.36) OPRL1OPRM1OPRK1TLR4CYP2C9
SCHEMBL17916601 0.84 OPRM1 (0.35) OPRL1OPRM1OPRK1TLR4CYP2C9
SCHEMBL20808413 0.82 OPRM1 (0.35) OPRL1OPRM1OPRK1TLR4
SCHEMBL20808415 0.82 OPRM1 (0.35) OPRL1OPRM1OPRK1TLR4
SCHEMBL20797235 0.82 OPRM1 (0.35) OPRL1OPRM1OPRK1TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679111-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-11-01 EP disclosed
US-20220228065-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2022-07-21 US disclosed
US-11326102-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2022-05-10 US disclosed
US-20200385636-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2020-12-10 US disclosed
EP-3679111-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2020-07-15 EP disclosed
CN-111094512-A Liquid crystal medium and liquid crystal display comprising same 默克专利股份有限公司 2020-05-01 CN disclosed
WO-2019048444-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed