Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909179 | 1.00 | OPRL1 (0.36) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL2909177 | 1.00 | OPRL1 (0.36) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL14494616 | 1.00 | OPRL1 (0.36) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL17916601 | 0.87 | OPRM1 (0.35) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL20808301 | 0.86 | OPRL1 (0.39) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL20808304 | 0.86 | OPRL1 (0.39) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL20797012 | 0.86 | OPRL1 (0.39) | OPRL1OPRM1OPRK1TLR4CYP2C9 | |
| SCHEMBL20808413 | 0.83 | OPRM1 (0.35) | OPRL1OPRM1OPRK1TLR4 | |
| SCHEMBL20808415 | 0.83 | OPRM1 (0.35) | OPRL1OPRM1OPRK1TLR4 | |
| SCHEMBL20797235 | 0.83 | OPRM1 (0.35) | OPRL1OPRM1OPRK1TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640433-B1 | CHROMAN DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-7226644-B2 | Chroman derivative and liquid-crystal composition containing the compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-06-05 | — | — | US | disclosed |
| US-20060163536-A1 | Chroman dervative and liquid-crystal composition containing the compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1640433-A1 | CHROMAN DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE COMPOUND | Dainippon Ink and Chemicals, Incorporated (JP) | 2006-03-29 | — | — | EP | disclosed |