Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29903417 | 1.00 | SCN4A (0.36) | SCN4AFDPSPRCPDPP7GLI1 | |
| SCHEMBL1371506 | 0.83 | SCN4A (0.38) | SCN4APRCPDPP7GLI1L3MBTL1 | |
| SCHEMBL24390695 | 0.75 | FDPS (0.35) | FDPSL3MBTL1MEN1KMT2AMITF | |
| SCHEMBL11663943 | 0.72 | SCN4A (0.41) | SCN4APRCPDPP7GLI1SLC6A2 | |
| SCHEMBL11661741 | 0.72 | PRCP (0.40) | SCN4APRCPDPP7GLI1MEN1 | |
| SCHEMBL18265386 | 0.71 | SCN4A (0.43) | SCN4APRCPDPP7GLI1 | |
| SCHEMBL21677068 | 0.71 | L3MBTL1 (0.50) | PRCPDPP7L3MBTL1MEN1KMT2A | |
| SCHEMBL5806646 | 0.71 | SCN4A (0.41) | SCN4AFDPSPRCPDPP7GLI1 | |
| SCHEMBL2917600 | 0.70 | GLI1 (0.58) | SCN4AFDPSPRCPDPP7GLI1 | |
| SCHEMBL16992331 | 0.70 | GLI1 (0.58) | SCN4AFDPSPRCPDPP7GLI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847161-A1 | ALTERNATIVE PROCESSES FOR THE PREPARATION OF TUBULYSINS AND INTERMEDIATES THEREOF | Seagen Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3679036-A1 | PROCESS FOR THE PREPARATION OF TUBULYSINS AND INTERMEDIATES THEREOF | Seattle Genetics, Inc. (US) | 2020-07-15 | — | — | EP | disclosed |
| WO-2019051322-A1 | PROCESS FOR THE PREPARATION OF TUBULYSINS AND INTERMEDIATES THEREOF | SEATTLE GENETICS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |