Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 2/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15947604 | 0.78 | ABCB1 (0.50) | ABCB1L3MBTL1PTPRB | |
| SCHEMBL20800061 | 0.78 | ABCB1 (0.50) | ABCB1L3MBTL1PTPRB | |
| SCHEMBL20800074 | 0.78 | GBA1 (0.38) | ABCB1L3MBTL1 | |
| SCHEMBL18764773 | 0.78 | HDAC3 (0.43) | MEN1GAAKMT2AHDAC3HDAC1 | |
| SCHEMBL6502917 | 0.77 | L3MBTL1 (0.44) | MEN1GAAKMT2ABCHESTK17B | |
| SCHEMBL6492075 | 0.77 | L3MBTL1 (0.44) | MEN1GAAKMT2ABCHESTK17B | |
| SCHEMBL7609410 | 0.77 | L3MBTL1 (0.44) | MEN1GAAKMT2ABCHESTK17B | |
| SCHEMBL22154278 | 0.76 | ABCB1 (0.52) | ABCB1KMT2AL3MBTL1PTPRB | |
| SCHEMBL14019980 | 0.76 | ABCB1 (0.52) | ABCB1KMT2AL3MBTL1PTPRB | |
| SCHEMBL18764937 | 0.76 | HDAC3 (0.46) | MEN1GAAKMT2AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051322-A1 | PROCESS FOR THE PREPARATION OF TUBULYSINS AND INTERMEDIATES THEREOF | SEATTLE GENETICS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |