Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502917 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL6492075 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL30416126 | 0.85 | MEN1 (0.47) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL30415110 | 0.84 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL6674923 | 0.81 | ADAM17 (0.43) | L3MBTL1MEN1KMT2AGAAADAM17 | |
| SCHEMBL2084864 | 0.80 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL20799996 | 0.77 | ABCB1 (0.43) | L3MBTL1MEN1KMT2AGAATDP1 | |
| SCHEMBL20309177 | 0.76 | GBA1 (0.38) | METAP1 | |
| SCHEMBL3654698 | 0.76 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AGAAMETAP1 | |
| SCHEMBL21751628 | 0.75 | MEN1 (0.47) | L3MBTL1MEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263711-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062704-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |