Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180605 | 0.84 | MCL1 (0.43) | ALDH1A1HIF1AHSD17B10HPGDTSHR | |
| SCHEMBL5019771 | 0.81 | KDM4E (0.49) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL18907601 | 0.79 | GPR3 (0.44) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL13706288 | 0.79 | CYP11B1 (0.44) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL16303040 | 0.78 | CYP11B1 (0.43) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL18819937 | 0.78 | MEN1 (0.40) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL18820551 | 0.78 | ALDH1A1 (0.53) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL18820514 | 0.78 | ALDH1A1 (0.49) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL24178521 | 0.77 | CYP11B1 (0.42) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD | |
| SCHEMBL14101680 | 0.77 | CYP1A2 (0.47) | CYP11B1ALDH1A1HIF1AHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2628742-B1 | ORGANIC ELECTRONIC DEVICE COMPRISING CHALCOGEN-CONTAINING AROMATIC COMPOUND | NIPPON STEEL CHEMICAL & MAT CO LTD (JP) | 2019-03-13 | — | — | EP | disclosed |