SCHEMBL20801124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18069149	0.96	TDP1 (0.42)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL21650722	0.94	KDM4E (0.41)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL18069139	0.87	TDP1 (0.39)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL18069153	0.84	KDM4E (0.36)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL20801123	0.84	TDP1 (0.50)	TDP1KDM4EKMT2AMEN1CYP1B1
	SCHEMBL22187988	0.83	KCNH2 (0.34)	TDP1MAPTKMT2AMEN1KCNH2
	SCHEMBL19791320	0.81	TDP1 (0.47)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL18069178	0.80	MEN1 (0.39)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL23592285	0.80	TDP1 (0.46)	TDP1KDM4EALDH1A1HPGDMAPT
	SCHEMBL23592282	0.79	TDP1 (0.46)	TDP1KDM4EALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.